A new duck genome reveals conserved and convergently evolved chromosome architectures of birds and mammals.

ABSTRACT:

Background

Ducks have a typical avian karyotype that consists of macro- and microchromosomes, but a pair of much less differentiated ZW sex chromosomes compared to chickens. To elucidate the evolution of chromosome architectures between ducks and chickens, and between birds and mammals, we produced a nearly complete chromosomal assembly of a female Pekin duck by combining long-read sequencing and multiplatform scaffolding techniques.

Results

A major improvement of genome assembly and annotation quality resulted from the successful resolution of lineage-specific propagated repeats that fragmented the previous Illumina-based assembly. We found that the duck topologically associated domains (TAD) are demarcated by putative binding sites of the insulator protein CTCF, housekeepi

SUBMITTER: Li J 

PROVIDER: S-EPMC7787181 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature