Characteristics and clinical outcomes of culture-negative and culture-positive septic shock: a single-center retrospective cohort study.

ABSTRACT:

Background

We evaluated the characteristics and outcomes of culture-negative versus culture-positive septic shock.

Methods

We performed a retrospective observational study of data from a prospective registry from 2014 to 2018. A total of 2,499 adult patients with septic shock were enrolled. The primary outcome was 90-day mortality, and the secondary outcomes were the length of hospital stay, a requirement for mechanical ventilation or renal replacement therapy, and in-hospital mortality.

Results

Of 1,718 patients with septic shock, 1,012 (58.9%) patients were culture-positive (blood 803, urine 302, sputum 102, others 204) and the median pathogen detection time was 9.5 h (aerobic 10.2 h and anaerobic 9.0 h). The most common site of culture-positive infection was the he

SUBMITTER: Kim JS 

PROVIDER: S-EPMC7787242 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature