The Survival Advantage of Females at Premenopausal Age Is Race Dependent in Colorectal Cancer.

ABSTRACT:

Background

A female prognostic advantage in younger individuals has been demonstrated in various cancers. Several large-scale analyses based on different racial backgrounds have reported inconsistent results in colorectal cancer. The aim of the present study was to evaluate the prognostic value of sex and age in patients with colorectal cancer of different ethnic groups.

Methods

We identified 71,812 eligible patients from the Surveillance, Epidemiology and End Results database. According to age at diagnosis, the patients were categorized into premenopausal age (≤45 yrs), menopausal age (46-54 yrs), and postmenopausal age (≥55 yrs) subgroups for further analysis.

Results

Multivariate analysis identified the female survival advantage to be significant in the premenopaus

SUBMITTER: Sheng H 

PROVIDER: S-EPMC7787739 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature