Healthspan Improvements in Caenorhabditis elegans with Traditional Chinese Herbal Tea.

ABSTRACT: Searching for natural and safe herbal tea with health benefits has attracted more and more attention, which is of great significance for reducing disease risk. A Chinese traditional herbal tea (HT) is rich in active ingredients extracted from natural plants. Numerous pharmacological studies showed that HT had the potential to improve health, including antidepression and antioxidant effects. In this study, we proposed a strategy to explore the role and underlying mechanism of HT in improving healthspan of a Caenorhabditis elegans model. First, we found that HT significantly prolonged the lifespan without reducing fertility in worms. Second, stress resistance (oxidative stress and heat stress) was enhanced and Aβ- and polyQ-induced toxicity was relieved significantly by HT trea

SUBMITTER: Lin C 

PROVIDER: S-EPMC7787765 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature