Microbial risk assessment of Nocardia cyriacigeorgica in polluted environments, case of urban rainfall water.

ABSTRACT: Urban Infiltration Basins (UIBs) are used to manage urban runoff transfers and feed aquifers. These UIBs can accumulate urban pollutants and favor the growth of potentially pathogenic biological agents as Nocardia.

Objectives

To assess the spatio-temporal dynamics of pathogenic Nocardia in UIBs and to stablish phylogenetic relationships between clinical and UIB N. cyriacigeorgica strains. To assess pathogenicity associated with environmental N. cyriacigeorgica using an animal model, and to identify genetic elements that may be associated to its virulence.

Methods

A well-characterized UIB in terms of chemical pollutants from Lyon area was used in this study during a whole year. Cultural and Next-Generation-Sequencing methods were used for Nocardi

SUBMITTER: Vautrin F 

PROVIDER: S-EPMC7787915 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature