Adult medical emergency unit presentations due to adverse drug reactions in a setting of high HIV prevalence.

ABSTRACT:

Introduction

South Africa has the world's largest antiretroviral treatment programme, which may contribute to the adverse drug reaction (ADR) burden. We aimed to determine the proportion of adult non-trauma emergency unit (EU) presentations attributable to ADRs and to characterise ADR-related EU presentations, stratified according to HIV status, to determine the contribution of drugs used in management of HIV and its complications to ADR-related EU presentations, and identify factors associated with ADR-related EU presentation.

Methods

We conducted a retrospective folder review on a random 1.7% sample of presentations over a 12-month period in 2014/2015 to the EUs of two hospitals in Cape Town, South Africa. We identified potential ADRs with the help of a trigger tool. A mul

SUBMITTER: Mouton JP 

PROVIDER: S-EPMC7787921 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature