OnabotulinumtoxinA is a well tolerated and effective treatment for refractory overactive bladder in real-world practice.

ABSTRACT:

Introduction and hypothesis

In randomized clinical trials onabotulinumtoxinA was demonstrated to be an effective and well-tolerated treatment for overactive bladder (OAB) with urinary incontinence (UI). However, data reporting onabotulinumtoxinA use in everyday clinical practice are limited. Here, we present the results from a large, first-of-its-kind real-world study in patients with OAB.

Methods

This was a prospective, observational, multinational study (GRACE; ClinicalTrials.gov , NCT02161159) performed in four European countries. Patients (N = 504) aged ≥ 18 years with OAB inadequately managed with ≥ 1 anticholinergic received onabotulinumtoxinA per their physician's normal clinical practice.

Results

Physicians primarily used rigid cystoscopes for onabotulinumtoxi

SUBMITTER: Hamid R 

PROVIDER: S-EPMC7788019 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature