Clinical characteristics and poor predictors of anti-NXP2 antibody-associated Chinese JDM children.

ABSTRACT:

Background

Juvenile dermatomyositis (JDM) is a rare and sometimes fatal disease in children. The anti-NXP2 antibody is one of the most common antibodies and muscle ischaemia associated with NXP2 autoantibodies was a severe subtype of JDM. Further information is needed regarding clinical characteristics and factors associated with poor prognosis. But there are no reports about clinical characteristics and high risk factor of poor prognosis. For the first time, we introduced the clinical characteristics and poor predictors of anti-NXP2 antibody-associated juvenile dermatomyositis in Chinese children.

Methods

Twenty-six patients with anti-NXP2 antibody-related JDM from 85 JDM Chinese patients were diagnosed from January 2016 to November 2019. Logistic regression was used to ana

SUBMITTER: Wang X 

PROVIDER: S-EPMC7788734 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature