Runs of homozygosity analysis of South African sheep breeds from various production systems investigated using OvineSNP50k data.

ABSTRACT:

Background

Population history, production system and within-breed selection pressure impacts the genome architecture resulting in reduced genetic diversity and increased frequency of runs of homozygosity islands. This study tested the hypothesis that production systems geared towards specific traits of importance or natural or artificial selection pressures influenced the occurrence and distribution of runs of homozygosity (ROH) in the South African sheep population. The Illumina OvineSNP50 BeadChip was used to genotype 400 sheep belonging to 13 breeds from South Africa representing mutton, pelt and mutton and wool dual-purpose breeds, including indigenous non-descript breeds that are reared by smallholder farmers. To get more insight into the autozygosity and distribution of ROH i

SUBMITTER: Dzomba EF 

PROVIDER: S-EPMC7788743 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature