Cost-related medication nonadherence in Canada: a systematic review of prevalence, predictors, and clinical impact.

ABSTRACT:

Background

Cost-related nonadherence to medications (CRNA) is common in many countries and thought to be associated with adverse outcomes. The characteristics of CRNA in Canada, with its patchwork coverage of increasingly expensive medications, are unclear.

Objectives

Our objective in this systematic review was to summarize the literature evaluating CRNA in Canada in three domains: prevalence, predictors, and effect on clinical outcomes.

Methods

We searched MEDLINE, Embase, Google Scholar, and the Cochrane Library from 1992 to December 2019 using search terms covering medication adherence, costs, and Canada. Eligible studies, without restriction on design, had to have original data on at least one of the three domains specifically for Canadian participants. Articles w

SUBMITTER: Holbrook AM 

PROVIDER: S-EPMC7788798 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature