Gastroesophageal reflux disease is a risk factor for sputum production in the general population: the Nagahama study.

ABSTRACT:

Background

Chronic sputum production in the general population is historically associated with clinical indices including male sex and smoking history. However, its relationship with gastroesophageal reflux disease (GERD), which may prove an underlying factor in sputum production, is unclear. We aimed to clarify factors associated with sputum production in the general population in cross-sectional and longitudinal manners.

Methods

In the Nagahama study, a community-based cohort study, 9804 subjects were recruited between 2008 and 2010 (baseline assessment), 8293 of whom were followed from 2013 to 2015 (follow-up assessment). This study contained a self-completed questionnaire which included medical history, assessment of sputum production, and a frequency scale for symptoms

SUBMITTER: Morimoto C 

PROVIDER: S-EPMC7788913 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature