Comparative transcriptome analysis uncovers roles of hydrogen sulfide for alleviating cadmium toxicity in Tetrahymena thermophila.

ABSTRACT:

Background

Cadmium (Cd) is a nonessential heavy metal with potentially deleterious effects on different organisms. The organisms have evolved sophisticated defense system to alleviate heavy metal toxicity. Hydrogen sulfide (H₂S) effectively alleviates heavy metal toxicity in plants and reduces oxidative stress in mammals. However, the function of H₂S for alleviating heavy metal toxicity in aquatic organisms remains less clear. Tetrahymena thermophila is an important model organism to evaluate toxic contaminants in an aquatic environment. In this study, the molecular roles of exogenously H₂S application were explored by RNA sequencing under Cd stress in T. thermophila.

Results

The exposure of 30 μM Cd resulted in T. thermophila growth inhibiti

SUBMITTER: Lv H 

PROVIDER: S-EPMC7788932 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature