Association of gestational diabetes mellitus with offspring weight status across infancy: a prospective birth cohort study in China.

ABSTRACT:

Background

The association between gestational diabetes mellitus (GDM) and childhood body weight remains controversial, and additional study is needed, especially in Asian populations.

Methods

This prospective study investigated the association between maternal glucose concentration, and GDM status and infant body weight from birth to 12 months of age. Linear mixed effects (LME) models and multiple linear regression were used to assess the longitudinal association of GDM with infant growth measured by weight-for-length z-scores (WFLZ), weight-for-age z-scores (WFAZ), and length-for-age z-scores (LFAZ) at birth, 1, 3, 6, 8, and 12 months of age.

Results

Offspring born to mothers with GDM had higher WFLZ [β: 0.26 SD units (95% CI: 0.13-0.40)] across infancy than those o

SUBMITTER: Hu J 

PROVIDER: S-EPMC7789150 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature