Ion channel profiling of the Lymnaea stagnalis ganglia via transcriptome analysis.

ABSTRACT:

Background

The pond snail Lymnaea stagnalis (L. stagnalis) has been widely used as a model organism in neurobiology, ecotoxicology, and parasitology due to the relative simplicity of its central nervous system (CNS). However, its usefulness is restricted by a limited availability of transcriptome data. While sequence information for the L. stagnalis CNS transcripts has been obtained from EST libraries and a de novo RNA-seq assembly, the quality of these assemblies is limited by a combination of low coverage of EST libraries, the fragmented nature of de novo assemblies, and lack of reference genome.

Results

In this study, taking advantage of the recent availability of a preliminary L. stagnalis genome, we generated an RNA-seq library from the adult L. stagnalis CNS, using a c

SUBMITTER: Dong N 

PROVIDER: S-EPMC7789530 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature