Menstrual, reproductive and hormonal factors and thyroid cancer: a hospital-based case-control study in China.

ABSTRACT:

Background

There have been considerable studies on the effects of reproductive factors on thyroid cancer risk, while findings are inconsistent. In this analysis, we aimed to investigate the associations between menstrual, reproductive and hormonal factors with thyroid cancer occurrence in a population of Chinese women.

Methods

Using data from a 1:1 matched case-control study performed between 2015 and 2017 in Zhejiang Province of China, a second analysis of 2261 pairs of female subjects was conducted. The possible effects for thyroid cancer were evaluated in logistic regression models by odds ratios (ORs) with 95% confidence intervals (CIs).

Results

Later age at first pregnancy (for > 25 vs. ≦ 20 years, OR: 0.47, 95% CI 0.23-0.96) and longer duration of breast feeding

SUBMITTER: Wang M 

PROVIDER: S-EPMC7789638 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature