Lifestyle modifications result in alterations in the gut microbiota in obese children.

ABSTRACT:

Background

The association between the gut microbiota and pediatric obesity was analyzed in a cross-sectional study. A prospective study of obese children was conducted to assess the gut microbial alterations after a weight change. We collected fecal samples from obese children before and after a 2-month weight reduction program that consisted of individual counseling for nutritional education and physical activity, and we performed 16S rRNA gene amplicon sequencing using an Illumina MiSeq platform.

Results

Thirty-six participants, aged 7 to 18 years, were classified into the fat loss (n = 17) and the fat gain (n = 19) groups according to the change in total body fat (%) after the intervention. The baseline analysis of the gut microbiota in the preintervention stages showed

SUBMITTER: Cho KY 

PROVIDER: S-EPMC7789654 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature