Personalized treatments for depressive symptoms in patients with advanced heart failure: A pragmatic randomized controlled trial.

ABSTRACT:

Objectives

Heart Failure is a chronic syndrome affecting over 5.7 million in the US and 26 million adults worldwide with nearly 50% experiencing depressive symptoms. The objective of the study is to compare the effects of two evidence-based treatment options for adult patients with depression and advanced heart failure, on depressive symptom severity, physical and mental health related quality of life (HRQoL), heart-failure specific quality of life, caregiver burden, morbidity, and mortality at 3, 6 and 12-months.

Methods

Trial design. Pragmatic, randomized, comparative effectiveness trial. Interventions. The treatment interventions are: (1) Behavioral Activation (BA), a patient-centered psychotherapy which emphasizes engagement in enjoyable and valued personalized activitie

SUBMITTER: IsHak WW 

PROVIDER: S-EPMC7790529 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature