CHOmics: A web-based tool for multi-omics data analysis and interactive visualization in CHO cell lines.

ABSTRACT: Chinese hamster ovary (CHO) cell lines are widely used in industry for biological drug production. During cell culture development, considerable effort is invested to understand the factors that greatly impact cell growth, specific productivity and product qualities of the biotherapeutics. While high-throughput omics approaches have been increasingly utilized to reveal cellular mechanisms associated with cell line phenotypes and guide process optimization, comprehensive omics data analysis and management have been a challenge. Here we developed CHOmics, a web-based tool for integrative analysis of CHO cell line omics data that provides an interactive visualization of omics analysis outputs and efficient data management. CHOmics has a built-in comprehensive pipeline for RNA sequencing data

SUBMITTER: Lin D 

PROVIDER: S-EPMC7790544 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature