Unknown

Dataset Information

0

CtDNA applications and integration in colorectal cancer: an NCI Colon and Rectal-Anal Task Forces whitepaper.


ABSTRACT: An increasing number of studies are describing potential uses of circulating tumour DNA (ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly developing area of research, the Colon and Rectal-Anal Task Forces of the United States National Cancer Institute convened a panel of multidisciplinary experts to summarize current data on the utility of ctDNA in the management of colorectal cancer and to provide guidance in promoting the efficient development and integration of this technology into clinical care. The panel focused on four key areas in which ctDNA has the potential to change clinical practice, including the detection of minimal residual disease, the management of patients with rectal cancer, monitoring responses to therapy, and tracking clonal dynamics in response to targeted therapies and other systemic treatments. The panel also provides general guidelines with relevance for ctDNA-related research efforts, irrespective of indication.

SUBMITTER: Dasari A 

PROVIDER: S-EPMC7790747 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

altmetric image

Publications

ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal-Anal Task Forces whitepaper.

Dasari Arvind A   Morris Van K VK   Allegra Carmen J CJ   Atreya Chloe C   Benson Al B AB   Boland Patrick P   Chung Ki K   Copur Mehmet S MS   Corcoran Ryan B RB   Deming Dustin A DA   Dwyer Andrea A   Diehn Maximilian M   Eng Cathy C   George Thomas J TJ   Gollub Marc J MJ   Goodwin Rachel A RA   Hamilton Stanley R SR   Hechtman Jaclyn F JF   Hochster Howard H   Hong Theodore S TS   Innocenti Federico F   Iqbal Atif A   Jacobs Samuel A SA   Kennecke Hagen F HF   Lee James J JJ   Lieu Christopher H CH   Lenz Heinz-Josef HJ   Lindwasser O Wolf OW   Montagut Clara C   Odisio Bruno B   Ou Fang-Shu FS   Porter Laura L   Raghav Kanwal K   Schrag Deborah D   Scott Aaron J AJ   Shi Qian Q   Strickler John H JH   Venook Alan A   Yaeger Rona R   Yothers Greg G   You Y Nancy YN   Zell Jason A JA   Kopetz Scott S  

Nature reviews. Clinical oncology 20200706 12


An increasing number of studies are describing potential uses of circulating tumour DNA (ctDNA) in the care of patients with colorectal cancer. Owing to this rapidly developing area of research, the Colon and Rectal-Anal Task Forces of the United States National Cancer Institute convened a panel of multidisciplinary experts to summarize current data on the utility of ctDNA in the management of colorectal cancer and to provide guidance in promoting the efficient development and integration of thi  ...[more]

Similar Datasets

| S-EPMC9360467 | biostudies-literature
| S-EPMC5290136 | biostudies-literature
| S-EPMC7147422 | biostudies-literature
| S-EPMC9397642 | biostudies-literature
| S-EPMC10020810 | biostudies-literature
| S-EPMC1727421 | biostudies-other
| S-EPMC2442470 | biostudies-literature
| S-EPMC6232522 | biostudies-literature
| S-EPMC4751169 | biostudies-literature
| S-EPMC6615556 | biostudies-literature