Biomarkers for Estimating Risk of Hospital Mortality and Long-Term Quality-of-Life Morbidity After Surviving Pediatric Septic Shock: A Secondary Analysis of the Life After Pediatric Sepsis Evaluation Investigation.

ABSTRACT:

Objectives

The Life After Pediatric Sepsis Evaluation investigation recently reported that one-third of children who survive sepsis experience significant health-related quality-of-life impairment compared with baseline at 1 year after hospitalization. Pediatric Sepsis Biomarker Risk Model is a multibiomarker tool for estimating baseline risk of mortality among children with septic shock. We determined if the Pediatric Sepsis Biomarker Risk Model biomarkers have predictive capacity for estimating the risk of hospital mortality and long-term health-related quality-of-life morbidity among children with community-acquired septic shock.

Design

Secondary analysis.

Setting

Twelve academic PICUs.

Patients

A subset of Life After Pediatric Sepsis Evaluation subjects (n

SUBMITTER: Wong HR 

PROVIDER: S-EPMC7790971 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature