Optimizing the impact of medications for opioid use disorder at release from prison and jail settings: A microsimulation modeling study.

ABSTRACT:

Background

We examined the impact of expanded access to medications for opioid use disorder (MOUD) in a unified prison and jail system on post-release, opioid-related overdose mortality.

Methods

We developed a microsimulation model to simulate a population of 55,000 persons at risk of opioid-related overdose mortality in Rhode Island. The effect of an extended-release (XR) naltrexone only intervention and the effect of providing access to all three MOUD (i.e., methadone, buprenorphine, and XR-naltrexone) at release from incarceration on cumulative overdose death over eight years (2017-2024) were compared to the standard of care (i.e., limited access to MOUD).

Results

In the standard of care scenario, the model predicted 2385 opioid-related overdose deaths between 2017

SUBMITTER: Macmadu A 

PROVIDER: S-EPMC7790977 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature