Higher Monocyte Count is Associated with 30-Day Case Fatality in Intracerebral Hemorrhage.

ABSTRACT:

Background

Previous studies have suggested that elevated neutrophils, monocytes, and neutrophil-to-lymphocyte ratio (NLR) may be associated with poor outcomes in intracerebral hemorrhage (ICH). We sought to determine whether white blood cell (WBC) types were independently associated with poor outcome in ICH in a large cohort.

Methods

We performed a retrospective study of primary ICH at two academic centers. Cases were identified via ICD-9 code and verified via physician review. We included only those patients with WBC types obtained within 24 h of ICH onset.

Results

We identified 593 patients with primary ICH and WBC differentials in the first 24 h. Independent factors (OR, 95% CI) associated with 30-day case fatality were age > 80 (2.4 (1.4, 4.2)), p = 0.0023; NIHSS

SUBMITTER: Mackey J 

PROVIDER: S-EPMC7791001 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature