Cross-sectional analysis of the association between serum uric acid levels and handgrip strength among Chinese adults over 45 years of age.

ABSTRACT:

Background

Sarcopenia is the decline in muscle strength and mass attributed to aging. The pathogenesis of sarcopenia may be triggered by oxidative stress; uric acid (UA) has strong antioxidant properties. This study aimed to examine if the serum UA level is associated with handgrip strength (HGS), which is a useful indicator of sarcopenia among Chinese participants aged over 45.

Methods

Our study included 992 eligible participants (583 males and 409 females). Based on serum UA quartiles and gender, the participants were divided into 8 groups. HGS was measured in kilograms using an electronic dynamometer. Face-to-face visits and fasting blood analyses were performed to determine the serum UA levels and various covariates. Univariate analysis of variance (ANOVA) and covariance

SUBMITTER: Xu L 

PROVIDER: S-EPMC7791196 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature