Comparison of different surgical interventions for hepatocellular carcinoma with bile duct tumor thrombus: a systematic review and meta-analysis.

ABSTRACT:

Background

The optimal surgical modality for hepatocellular carcinoma (HCC) with bile duct tumor thrombus (BDTT) remains controversial, especially regarding deciding whether to perform concurrent bile duct resection (BDR).

Methods

PubMed, EMBASE, Cochrane Library, Web of Science and Scopus databases were systematically searched from inception to February 2020, in order to compare overall survival (OS) and recurrence-free survival (RFS) rates of HCC patients with BDTT who had either received hepatectomy with extrahepatic bile duct resection (BDR group) or hepatectomy without bile duct resection (NBDR group). Relevant outcomes were extracted by two investigators.

Results

A total of 12 studies involving 355 patients was included. The 1-, 3- and 5-year OS rates were simil

SUBMITTER: Feng JK 

PROVIDER: S-EPMC7791268 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature