Visualization of left ventricular Purkinje fiber distribution using widefield optical coherence microscopy.

ABSTRACT:

Background

The distribution and connection of ventricular Purkinje fibers are known to be associated with idiopathic left ventricular arrhythmias. Unusual anatomy is one of the important factors associated with catheter ablation success rate. With the widefield high-speed, swept-source optical coherence microscopy (OCM) and light microscope, we visualized the left ventricular Purkinje fiber distribution.

Methods

Left ventricular walls of five adult ovine hearts were incised from the mitral annulus to the apex. Using the widefield OCM technique and light microscopy, we observed the distribution, direction, depth, and dividing patterns of the Purkinje network with multiple tangential angles and without tissue destruction.

Results

Widefield OCM was used to characterize t

SUBMITTER: Cha MJ 

PROVIDER: S-EPMC7791375 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature