Long-Term Prognostication for 20 114 Women With Small and Node-Negative Breast Cancer (T1abN0).

ABSTRACT:

Background

Although small, node-negative breast cancer (ie, T1abN0) constitutes 20% of all newly diagnosed breast cancers, data on prognosis and prognostic factors are limited.

Methods

We conducted a population-based cohort study including 20 114 Swedish women treated for T1abN0 breast cancer from 1977 onward. Patient and tumor data were collected from Swedish breast cancer registries. Cohort subjects were followed through linkage to the Cause of Death Register. We calculated the cumulative incidence of breast cancer-specific and overall death and used Cox regression to estimate hazard ratios (HRs) and 95% confidence intervals (CIs).

Results

During a median follow-up of 9.1 years (range = 0-38), 915 women died of breast cancer and 5416 of any cause. The 10-, 20-, and

SUBMITTER: Jaraj D 

PROVIDER: S-EPMC7791632 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature