Serological diagnosis and prevalence of HIV-1 infection in Russian metropolitan areas.

ABSTRACT:

Background

HIV infection is a major health problem in Russia. We aimed to assess HIV prevalence in different population groups and to compare the characteristics of 4th generation immunoassays from Abbott, Bio-Rad, Vector-Best, Diagnostic Systems, and Medical Biological Unit.

Methods

The study included 4452 individuals from the general population (GP), 391 subjects at high risk of HIV infection (HR) and 699 with potentially interfering conditions. HIV positivity was confirmed by immunoblot and by HIV RNA, seroconversion and virus diversity panels were also used. HIV avidity was employed to assess recent infections.

Results

The prevalence in GP was 0.40%, higher in males (0.62%) and in people aged < 40 years (0.58%). Patients attending dermo-venereal centers and drug u

SUBMITTER: Kireev DE 

PROVIDER: S-EPMC7791727 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature