Redox-sensitive polymeric micelles with aggregation-induced emission for bioimaging and delivery of anticancer drugs.

ABSTRACT:

Background

Nano-drug delivery systems show considerable promise for effective cancer therapy. Polymeric micelles have attracted extensive attention as practical nanocarriers for target drug delivery and controlled drug delivery system, however, the distribution of micelles and the release of the drug are difficult to trace in cancer cells. Therefore, the construction of a redox-sensitive multifunctional drug delivery system for intelligent release of anticancer drugs and simultaneous diagnostic imaging and therapy remains an attractive research subject.

Results

To construct a smart drug delivery system for simultaneous imaging and cancer chemotherapy, mPEG-ss-Tripp was prepared and self-assembled into redox-sensitive polymeric micelles with a diameter of 105 nm that were eas

SUBMITTER: Sun C 

PROVIDER: S-EPMC7791786 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature