Green coffee methanolic extract and silymarin protect against CCl4-induced hepatotoxicity in albino male rats.

ABSTRACT:

Background

During the last few decades, patients worldwide have been interested in using alternative medicine in treating diseases to avoid the increased side effects of chemical medications. Green coffee is unroasted coffee seeds that have higher amounts of chlorogenic acid compared to roasted coffee. Green coffee was successfully used to protect against obesity, Alzheimer disease, high blood pressure and bacterial infection.

Methods

This study aimed to investigate the probable protective activity of the green coffee methanolic extract, silymarin and their combination on CCl₄-induced liver toxicity in male rats. Thirty Sprague - Dawley male albino rats were divided into 5 groups; control negative (G1) just got the vehicle (olive oil) and the other four groups rec

SUBMITTER: El Rabey HA 

PROVIDER: S-EPMC7792057 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature