Functional Capacity Past Age 40 in Patients With Congenital Ventricular Septal Defects.

ABSTRACT: Background Ventricular septal defects (VSD), when treated correctly in childhood, are considered to have great prognoses, and the majority of patients are discharged from follow-up when entering their teens. Young adults were previously found to have poorer functional capacity than healthy peers, but the question remains whether functional capacity degenerates further with age. Methods and Results A group of 30 patients with surgically closed VSDs (51±8 years) with 30 matched, healthy control participants (52±9 years) and a group of 30 patients with small unrepaired VSDs (55±12 years) and 30 matched control participants (55±10 years) underwent cardiopulmonary exercise testing using an incremental workload protocol and noninvasive gas measurement. Peak oxygen uptake was lower in participant

SUBMITTER: Maagaard M 

PROVIDER: S-EPMC7792429 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature