Evaluation of the national surveillance system for invasive meningococcal disease, Italy, 2015-2018.

ABSTRACT: Enhanced laboratory-based surveillance of invasive meningococcal disease (IMD) in Italy was only assessed indirectly by numerically comparing surveillance data cases with hospital discharge records (HDR). In this study, we evaluated the completeness, timeliness and sensitivity of the IMD surveillance in Italy from 2015 to 2018. Completeness and timeliness were described at the national and subnational level. A capture-recapture analysis was conducted to evaluate the sensitivity and positive predictive value (PPV) using HDR as the external source with a combination of deterministic and probabilistic approaches. The characteristics of the unmatched vs. matched cases were compared using multivariable Poisson modeling. Overall, the completeness of data improved, except for specific variables.

SUBMITTER: Andrianou XD 

PROVIDER: S-EPMC7793274 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature