Transcriptional Circuits Regulating Developmental Processes in Candida albicans.

ABSTRACT: Candida albicans is a commensal member of the human microbiota that colonizes multiple niches in the body including the skin, oral cavity, and gastrointestinal and genitourinary tracts of healthy individuals. It is also the most common human fungal pathogen isolated from patients in clinical settings. C. albicans can cause a number of superficial and invasive infections, especially in immunocompromised individuals. The ability of C. albicans to succeed as both a commensal and a pathogen, and to thrive in a wide range of environmental niches within the host, requires sophisticated transcriptional regulatory programs that can integrate and respond to host specific environmental signals. Identifying and characterizing the transcriptional regulatory networks that control i

SUBMITTER: Rodriguez DL 

PROVIDER: S-EPMC7793994 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature