Fractional anisotropy thresholding for deterministic tractography of the roots of the brachial plexus.

ABSTRACT: Diffusion tensor imaging (DTI) metrics, such as the fractional anisotropy (FA) and estimates of diffusivity are sensitive to the microstructure of peripheral nerves and may be displayed as tractograms. However, the ideal conditions for tractography of the roots of the brachial plexus are unclear, which represents the rationale for this study. Ten healthy adults were scanned using a Siemens Prisma (3T) and single-shot echo-planar imaging (b-value 0/1000 s/mm², 64 directions, 2.5 mm³ with 4 averages; repeated in opposing phase encoding directions). Susceptibility correction and tractography were performed in DSI Studio by two independent raters. The effect of FA thresholding at increments of 0.01 (from 0.04 to 0.10) were tested. The mean FA varied between subjects by 2%

SUBMITTER: Wade RG 

PROVIDER: S-EPMC7794285 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature