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A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb2Se9 using poloxamer.

ABSTRACT: In this research, dispersion of a new type of one-dimensional inorganic material Nb2Se9, composed of van der Waals bonds, in aqueous solution for bio-application study were studied. To disperse Nb2Se9, which exhibits hydrophobic properties in water, experiments were carried out using a block copolymer (poloxamer) as a dispersant. It was confirmed that PPO, the hydrophobic portion of Poloxamer, was adsorbed onto the surface of Nb2Se9, and PEO, the hydrophilic portion, induced steric hinderance to disperse Nb2Se9 to a size of 10 nm or less. To confirm the adaptability of muscle cells C2C12 to the dispersed Nb2Se9 using poloxamer 188 as dispersant, a MTT assay and a live/dead assay were performed, demonstrating improvement in the viability and proliferation of C2C12 cells.

SUBMITTER: Chae S 

PROVIDER: S-EPMC7794490 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb<sub>2</sub>Se<sub>9</sub> using poloxamer.

Chae Sudong S   Oh Seungbae S   Choi Kyung Hwan KH   Lee Jin Woong JW   Jeon Jiho J   Liu Zhixiang Z   Wang Cong C   Lim Changmo C   Dong Xue X   Woo Chaeheon C   Asghar Ghulam G   Shi Liyi L   Kang Joohoon J   Kim Sung Jae SJ   Song Si Young SY   Lee Jung Heon JH   Yu Hak Ki HK   Choi Jae-Young JY  

Scientific reports 20210108 1

In this research, dispersion of a new type of one-dimensional inorganic material Nb<sub>2</sub>Se<sub>9</sub>, composed of van der Waals bonds, in aqueous solution for bio-application study were studied. To disperse Nb<sub>2</sub>Se<sub>9</sub>, which exhibits hydrophobic properties in water, experiments were carried out using a block copolymer (poloxamer) as a dispersant. It was confirmed that PPO, the hydrophobic portion of Poloxamer, was adsorbed onto the surface of Nb<sub>2</sub>Se<sub>9</su  ...[more]

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