A Randomized Trial of Physical Activity in Children and Adolescents with Cancer.

ABSTRACT:

Background

to evaluate the safety and efficacy of a physical activity program (PAP) in children and adolescents with cancer.

Methods

children and adolescents with cancer were randomly assigned in a 1:1 ratio to the six-month PAP (intervention group) or to the control group. The first evaluation was performed at the end of the PAP (T0 + 6 mo). At T0 + 6 mo, both groups received the six-month PAP with a second evaluation at T0 + 12 mo. The primary outcome was the evolution of exercise capacity measured using the six-minute walk test (6 MWT) at T0 + 6 mo. Secondary outcomes included PAP safety and changes in other physical functions, self-esteem, and quality-of-life parameters.

Results

The trial involved 80 children and adolescents (age range 5.0-18.4 years), of whom 41

SUBMITTER: Saultier P 

PROVIDER: S-EPMC7795208 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature