Synthesis and Biological Activity of Brassinosteroid Analogues with a Nitrogen-Containing Side Chain.

ABSTRACT: Brassinosteroids are a class of plant hormones that regulate a broad range of physiological processes such as plant growth, development and immunity, including the suppression of biotic and abiotic stresses. In this paper, we report the synthesis of new brassinosteroid analogues with a nitrogen-containing side chain and their biological activity on Arabidopis thaliana. Based on molecular docking experiments, two groups of brassinosteroid analogues were prepared with short and long side chains in order to study the impact of side chain length on plants. The derivatives with a short side chain were prepared with amide, amine and ammonium functional groups. The derivatives with a long side chain were synthesized using amide and ammonium functional groups. A total of 25 new brassinoster

SUBMITTER: Diachkov MV 

PROVIDER: S-EPMC7795425 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature