The Role of Cannabinoids as Anticancer Agents in Pediatric Oncology.

ABSTRACT: Cannabinoids are a group of chemicals that bind to receptors in the human body and, in turn, modulate the endocannabinoid system (ECS). They can be endogenously produced, synthetic, or derived from the plant Cannabis sativa L. Research over the past several decades has shown that the ECS is a cellular communication network essential to maintain multiple biological functions and the homeostasis of the body. Indeed, cannabinoids have been shown to influence a wide variety of biological effects, including memory, pain, reproduction, bone remodeling or immunity, to name a few. Unsurprisingly, given these broad physiological effects, alterations of the ECS have been found in different diseases, including cancer. In recent years, the medical use of cannabis has been approved in different

SUBMITTER: Andradas C 

PROVIDER: S-EPMC7796497 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature