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Major Urological Cancer Surgery for Patients is Safe and Surgical Training Should Be Encouraged During the COVID-19 Pandemic: A Multicentre Analysis of 30-day Outcomes.


ABSTRACT: COVID-19 has resulted in the deferral of major surgery for genitourinary (GU) cancers with the exception of cancers with a high risk of progression. We report outcomes for major GU cancer operations, namely radical prostatectomy (RP), radical cystectomy (RC), radical nephrectomy (RN), partial nephrectomy (PN), and nephroureterectomy performed at 13 major GU cancer centres across the UK between March 1 and May 5, 2020. A total of 598 such operations were performed. Four patients (0.7%) developed COVID-19 postoperatively. There was no COVID-19-related mortality at 30 d. A minimally invasive approach was used in 499 cases (83.4%). A total of 228 cases (38.1%) were described as training procedures. Training case status was not associated with a higher American Society of Anesthesiologists (ASA) score (p =  0.194) or hospital length of stay (LOS; p >  0.05 for all operation types). The risk of contracting COVID-19 was not associated with longer hospital LOS (p =  0.146), training case status (p =  0.588), higher ASA score (p =  0.295), or type of hospital site (p =  0.303). Our results suggest that major surgery for urological cancers remains safe and training should be encouraged during the ongoing COVID-19 pandemic provided appropriate countermeasures are taken. These real-life data are important for policy-makers and clinicians when counselling patients during the current pandemic.

Patient summary

We collected outcome data for major operations for prostate, bladder, and kidney cancers during the COVID-19 pandemic. These surgeries remain safe and training should be encouraged during the ongoing pandemic provided appropriate countermeasures are taken. Our real-life results are important for policy-makers and clinicians when counselling patients during the COVID-19 pandemic.

SUBMITTER: Tan WS 

PROVIDER: S-EPMC7796655 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

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Major Urological Cancer Surgery for Patients is Safe and Surgical Training Should Be Encouraged During the COVID-19 Pandemic: A Multicentre Analysis of 30-day Outcomes.

Tan Wei Shen WS   Arianayagam Rajan R   Khetrapal Pramit P   Rowe Edward E   Kearley Samantha S   Mahrous Ahmed A   Pal Raj R   Fowler William W   Heer Rakesh R   Elajnaf Mohamed M   Douglas-Moore Jayne J   Leyshon Griffiths T R TR   Voss James J   Wilby Daniel D   Al Kadhi Omar O   Noel Jonathan J   Vasdev Nikhil N   McKay Alastair A   Ahmad Imran I   Abu-Nayla Islam I   Lamb Benjamin B   Hill George T GT   Narahari Krishna K   Kynaston Howard H   Yousuf Arzu A   Kusuma Venkata R M VRM   Cresswell Jo J   Cooke Pete P   Chakravarti Aniruddha A   Barod Ravi R   Bex Axel A   Kelly John D JD  

European urology open science 20210109


COVID-19 has resulted in the deferral of major surgery for genitourinary (GU) cancers with the exception of cancers with a high risk of progression. We report outcomes for major GU cancer operations, namely radical prostatectomy (RP), radical cystectomy (RC), radical nephrectomy (RN), partial nephrectomy (PN), and nephroureterectomy performed at 13 major GU cancer centres across the UK between March 1 and May 5, 2020. A total of 598 such operations were performed. Four patients (0.7%) developed  ...[more]

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