Target value of mean arterial pressure in patients undergoing continuous renal replacement therapy due to acute kidney injury.

ABSTRACT:

Background

Although patients undergoing continuous renal replacement therapy (CRRT) due to acute kidney injury (AKI) frequently have instability in mean arterial pressure (MAP), no consensus exists on the target value of MAP related to high mortality after CRRT.

Methods

A total of 2,292 patients who underwent CRRT due to AKI in three referral hospitals were retrospectively reviewed. The MAPs were divided into tertiles, and the 3^rd tertile group served as a reference in the analyses. The major outcome was all-cause mortality during the intensive care unit period. The odds ratio (OR) of mortality was calculated using logistic regression after adjustment for multiple covariates. The nonlinear relationship regression model was applied to determine the threshold value

SUBMITTER: Kim Y 

PROVIDER: S-EPMC7796677 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature