Statistical Modelling of the Visual Impact of Subretinal Fluid and Associated Features.

ABSTRACT:

Introduction

The aim of this study was to develop a statistical model to determine the visual significance of subretinal fluid (SRF) in combination with other constructed optical coherence tomography (OCT) features in patients with wet age-related macular degeneration.

Methods

The project used labelled data from 1211 OCTs of patients with neovascular macular degeneration (nAMD) attending the macular treatment centre of Manchester Royal Eye Hospital to build a statistical model to determine vision for any virtual, constructed OCT. A four-dimensional plot was created to represent the visual impact of SRF in OCTs in the context of the associated OCT characteristics of atrophy and subretinal hyperreflective material (SHRM).

Results

The plot illustrates that at levels of S

SUBMITTER: Aslam TM 

PROVIDER: S-EPMC7796679 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature