Immuno-informatics approach for B-cell and T-cell epitope based peptide vaccine design against novel COVID-19 virus.

ABSTRACT: COVID-19 has brought the world to a standstill with a wave of destruction in country after country with tremendous loss of lives and livelihood in advanced to developing nations. Whole world is staring at the prospect of repeated lockdowns with another wave of COVID-19 predicted to hit the world in September of 2020. The second wave is assumed to be even more destructive with severe impact across much of the world. The only way to defeat this pandemic is to quickly develop a safe and effective vaccine against this raging menace and initiate a global vaccination drive. Our study is an attempt to deploy various computational methods to identify B-cell and T-cell epitopes from the spike surface glycoprotein of SARS-COV-2 which have the novel potential for vaccine development against COVID-19.

SUBMITTER: Singh J 

PROVIDER: S-EPMC7796797 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature