Principal Cause of Poor Visual Acuity after Neovascular Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report Number 23.

ABSTRACT:

Purpose

To analyze the principal cause for poor vision in eyes with best-corrected visual acuity (BCVA) of 20/200 or worse 2 years after neovascular age-related macular degeneration (nAMD).

Design

Prospective cohort study of participants enrolled in a clinical trial of oral supplements.

Participants

Age-Related Eye Disease Study 2 (AREDS2) participants whose eyes began anti-vascular endothelial growth factor (VEGF) therapy for incident nAMD and had data available at 2 years.

Methods

Participants underwent refracted BCVA testing, ophthalmoscopic examination, and fundus photography at baseline and annual visits. Self-reports of anti-VEGF injections were collected.

Main outcome measures

Principal cause of BCVA of 20/200 or worse at 2 years, detected on fund

SUBMITTER: Okeagu CU 

PROVIDER: S-EPMC7796863 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature