Association of Infant Antibiotic Exposure With Childhood Health Outcomes.

ABSTRACT:

Objective

To investigate the extent to which antibiotic exposure in the first 2 years of life is associated with the risk of immunological, metabolic, and neurobehavioral health conditions with childhood onset.

Patients and methods

In this population-based cohort study, we identified all children born in Olmsted County, Minnesota, between January 1, 2003, and December 31, 2011, through the Rochester Epidemiology Project medical records-linkage system. Demographic characteristics, antibiotic prescriptions, and diagnostic codes through June 30, 2017, were retrieved using the Rochester Epidemiology Project infrastructure. Time-to-event analysis was performed to assess the impact of antibiotic exposure on the risk of several adverse health conditions.

Results

This study i

SUBMITTER: Aversa Z 

PROVIDER: S-EPMC7796951 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature