Endometrial thickness after ovarian stimulation with gonadotropin, clomiphene, or letrozole for unexplained infertility, and association with treatment outcomes.

ABSTRACT:

Objective

To study the association of endometrial thickness (EMT) with live birth rates (LBR) in ovarian stimulation with intrauterine insemination (OS-IUI) treatments for unexplained infertility.

Design

Prospective cohort analysis of the Reproductive Medicine Network's Assessment of Multiple Intrauterine Gestations from Ovarian Stimulation (AMIGOS) randomized controlled trial.

Setting

Multicenter randomized controlled trial.

Patients

A total of 868 couples with unexplained infertility (n=2,459 cycles).

Interventions

OS-IUI treatment cycles (n = 2,459) as part of the AMIGOS clinical trial.

Main outcome measures

Live birth rates; unadjusted and adjusted risk ratios (RR) for live birth by EMT category, calculated using generalized estimating equatio

SUBMITTER: Quaas AM 

PROVIDER: S-EPMC7796980 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature