Factors associated with elevated alanine aminotransferase in employees of a German chemical company: results of a large cross-sectional study.

ABSTRACT:

Background

We aimed to determine the prevalence of elevated alanine aminotransferase (eALT) in employees of a German chemical company, and analyze its association with sociodemographic, work- and lifestyle-related factors.

Methods

The cross-sectional study is based on data surveyed from occupational health check-ups between 2013 and 2018 at the site clinic of a chemical company based in Ludwigshafen, Germany. We used logistic regression analyses to assess the association between sociodemographic, work- and lifestyle-related characteristics and eALT. Quantile regression technique was applied to investigate if associations vary across different quantiles of the ALT distribution.

Results

Participants (n = 15,348) were predominantly male (78.3%) with a mean age of 42.2 ye

SUBMITTER: Claus M 

PROVIDER: S-EPMC7797104 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature