Duration of diaphragmatic inactivity after endotracheal intubation of critically ill patients.

ABSTRACT:

Background

In patients intubated for mechanical ventilation, prolonged diaphragm inactivity could lead to weakness and poor outcome. Time to resume a minimal diaphragm activity may be related to sedation practice and patient severity.

Methods

Prospective observational study in critically ill patients. Diaphragm electrical activity (EAdi) was continuously recorded after intubation looking for resumption of a minimal level of diaphragm activity (beginning of the first 24 h period with median EAdi > 7 µV, a threshold based on literature and correlations with diaphragm thickening fraction). Recordings were collected until full spontaneous breathing, extubation, death or 120 h. A 1 h waveform recording was collected daily to identify reverse triggering.

Results

Seventy-fiv

SUBMITTER: Sklar MC 

PROVIDER: S-EPMC7798017 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature