Investment decisions in influenza pandemic contingency planning: cost-effectiveness of stockpiling antiviral drugs.

ABSTRACT:

Background

The threat of an influenza pandemic has led to stockpiling of antiviral drugs in order to mitigate a plausible outbreak. If the stockpile would be used in relation to the recent pandemic alert, an investment decision about renewing the stock for a possible subsequent pandemic is essential. The decision should include cost-effectiveness considerations.

Methods

We constructed a cost-effectiveness analysis in the Dutch context, explicitly including risk of an outbreak. Outcomes from a dynamic transmission model, comparing an intervention with a non-intervention scenario, were input in our health economic calculations.

Results

Stockpiling was cost-effective from the health-care perspective if the actual risk is 37% for 30 years. If less than 60% of the populati

SUBMITTER: Lugner AK 

PROVIDER: S-EPMC7798111 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature