Validation of the 8th lung cancer TNM classification and clinical staging system in a German cohort of surgically resected patients.

ABSTRACT:

Objectives

The updated 8th edition of the tumor, node, metastases (TNM) classification system for non-small cell lung cancer (NSCLC) attempts to improve on the previous 7th edition in predicting outcomes and guiding management decisions. This study sought to determine whether the 8th edition was more accurate in predicting long-term survival in a European population of surgically treated NSCLC patients.

Methods

We scanned the archives of the Heckeshorn Lung Clinic for patients with preoperative clinical stages of IIIA or lower (based on the 7th edition), who received surgery for NSCLC between 2009 and 2014. We used pathologists' reports and data on tumor size and location to reassign tumor stages according to the 8th edition. We then analyzed stage specific survival and comp

SUBMITTER: Taber S 

PROVIDER: S-EPMC7798301 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature