Elevated Testosterone Is Associated with Decreased Likelihood of Current Asthma Regardless of Sex.

ABSTRACT:

Background

Asthma prevalence decreases postpuberty in males. Testosterone inhibits airway smooth muscle contraction and attenuates type 2 inflammation.

Objective

To investigate the relationship between serum testosterone and current asthma prevalence and lung function in a nationally representative data set.

Methods

Serum testosterone and self-reported physician-diagnosed current asthma data were obtained from 7584 participants aged 6 to 80 years from the cross-sectional 2011-2012 National Health and Nutrition Examination Survey. We used logistic regression to test associations between testosterone and current asthma, adjusting for demographic characteristics and stratifying by sex and age; linear regression to evaluate correlations between testosterone and lung funct

SUBMITTER: Bulkhi AA 

PROVIDER: S-EPMC7798361 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature