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Early versus late acute kidney injury among patients with COVID-19-a multicenter study from Wuhan, China.


ABSTRACT:

Background

Acute kidney injury (AKI) is an important complication of coronavirus disease 2019 (COVID-19), which could be caused by both systematic responses from multi-organ dysfunction and direct virus infection. While advanced evidence is needed regarding its clinical features and mechanisms. We aimed to describe two phenotypes of AKI as well as their risk factors and the association with mortality.

Methods

Consecutive hospitalized patients with COVID-19 in tertiary hospitals in Wuhan, China from 1 January 2020 to 23 March 2020 were included. Patients with AKI were classified as AKI-early and AKI-late according to the sequence of organ dysfunction (kidney as the first dysfunctional organ or not). Demographic and clinical features were compared between two AKI groups. Their

SUBMITTER: Peng S 

PROVIDER: S-EPMC7798799 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature